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 | Anne Willem Holthe Tot Echten (1816-1900) |
 | Maria Louisa Hora-Buma (1820-1894) |
| Johannes van der Tuuk (1821-1883) |
| Catharina Uniken (1827-1904) |
| Johan Hora Holthe Tot Echten (1853-1918)
|
| Ellegonda Durandina van der Tuuk (1856-1927)
|
| Maria Louisa Holthe Tot Echten (1879- )  |
| Johannes Holthe Tot Echten (1880- ) |
| Anne Willem Holthe Tot Echten (1880- ) |
| Catharina Martha van Holthe Tot Echten (1884-1971) |